HUSAR Bioinformatics Lab
Deutsches Krebsforschungszentrum Genomics Proteomics Core Facility
Advanced Bioinformatics Workshop
 
Agenda
The aim of the advanced bioinformatics workshops is to bring you up to date with the different fields and latest developments in Bioinformatics. Exciting topics in Bioinformatics are reviewed. The advanced workshops (free of charge) discuss important programs and their underlying algorithms and include practical training sessions.

First Day

9:00 Introduction
9:10 Pairwise sequence alignment I

  • Principles of sequence comparison
  • Scoring Systems
  • Gap Penalties
  • Global Alignment
  • Local Alignment
9:45 Break
10:00 Pairwise sequence alignment II
  • Methods of sequence comparison
  • Window-based approaches
  • Dynamic programming-based approaches
  • Needleman-Wunsch / Smith-Waterman
10:45 Break
11:00 Multiple alignment
  • Approaches
  • Multidimensional dynamic programming
  • Progressive alignments
  • And others (DiAlign, Tcoffee, Muscle)

12:00 Lunch
14:00 Mapping of next generation sequence data
15:00 Break
15:15 Database searching I
  • FastA, Blast
16:00 Break
16:15 Database searching II
  • Strategies
  • Examples
17:00 End


Second Day

9:00 Exercises alignments - PC-Room Main Building
11:00 Break
11:30 Profiles and Hidden Markov models in Biology
12:30 Lunch
13:30 The ENSEMBL web interface

  • - Guided Tour
  • - Excercises
15:30 Break
15:45 Phylogeny
17:15 End

Register via the Mitarbeiterportal